Sickle cell disease is caused by a genetic mutation which turns normally soft, round red blood cells into stiff, sickle-shaped cells that frequently block small blood vessels, leading to debilitating pain, cumulative damage to body organs, and sometimes fatal strokes and heart attacks.

CHOP researchers are literally on the cusp of a cure for sickle cell disease, but we need your help. Donations to Hope on the Horizon will help us transform patients' lives and ultimately cure sickle cell disease. Donate now and join the fight for a cure.

Support the cause to fund a cure for Sickle Cell Disease by attending the Blue Tag Gala September 14th, 2013 at The Children's Hospital of Philadelphia.